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Generally, doxycycline is also given along with the adulticide to eliminate the Wolbachia parasite.
In addition to getting rid of the adult heartworms, veterinarians will also attack the microfilaria, using Ivermectin, which can also be used as a preventative treatment for heartworms.
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The other two doses of Immiticide are also given by injection.The adult heartworms – which can occupy the heart, lungs, and blood vessels – are killed with an adulticide.Melarsomine dihydrochloride, an arsenic-based poison, is sold under the name Immiticide.While not generally recommended, another method of handling heartworms is to only attack the microfilaria, leaving existing adult heartworms to die of natural causes. It’s cheaper and does not require the rest period and debilitating adulticide.However, adult heartworms are innately dangerous to dogs, and complications from their presence within your dog could occur.